pentobarbital will lower the level or effect of diazepam buccal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. Solid or reasonable CYP3A4 inducers could enhance amount of diazepam elimination; thus, efficacy of diazepam could possibly be lessened.pentobarbital will lessen the level or outcome of ibuprofen by impactin